Friday, August 30, 2013

More information about Crinum latifolium

Crinum latifolium, broadleaf crinum, broadleaf garlic, “Tây nam văn châu lan”, thailand garlic. In Chinese literature, they are called as “Vạn châu lan” or “Thập bát học sỹ - 18 students”; their scientific name is Crinum latifolium L. belonging to Crinum or Amaryllidacea class. 

Crinum latifolium is the herb that ancient doctors used to treat female virgin, and this gave rise to their name.

There plants originate from India, after that they are planted in the Southeast Asian countries such as Thailand, Laos, Malaysia, Vietnam and southern China.

Professor Ghosal, an Indian scientist analyzed the chemical composition of Crinum latifolium in 1984 - 1989 and he found some alkaloid derivatives that have the anti-cancer effects. He isolated from the Crinum latifolium flowers a Glucose alkaloid called Latisolin. He used enzymes to hydrolyze that substances and obtained aglycon, Ghosal, Shibnath; at the time he also isolated from the stems of the flowers 2 substances: pratorimin and pratosin, the new pyrrolophennanthridon alkaloids, and pratorimin, Ambelin and Lycorin. He published in 1986 a number of other alkaloid derivatives that have the anti-cancer effects. By 1989, he isolated the extracts from the Crinum latifolium flowers 2 other pyrrolophennanthridin alkaloids which are epilycorin and epipancrassidin. Some Japanese scientists such as Shigenru Kobayashi, Tomoda and Masashi also found some other alkaloids in Crinum latifolium. In India they use hot fried Crinum latifolium for topical use in joint pain medications, pimples, abscesses, leaves extract for ear pain.

Modern medicine has discovered in Vietnam’s Crinum latifolium many biologically active substances with the ability to stop the growth of tumor cells and stimulate the T lymphocyte activity and development. In addition, they found that Crinum latifolium L. contains substances that can actively support the treatment of benign prostate hyperplasia and uterine fibroids and inhibit the growth of cancer cells such as Crinafolidine, Crinafoline, and Paratorimin. While there are 12 Crinum latifolium variants, all of them belong to the Crinum class, but they have different effects, i.e. In addition to the effects of Vietnam’ Crinum latifolium, the Cambodia’s Crinum latifolium also owns the contraceptive properties. Furthermore, there's also a number of other plants that have similar appearance to Vietnam’s Crinum latifolium but they contains many toxic properties. They can be used along with the Crinoidea, Crinum asiaticum L., or other crinum that is similar to the Crinum latifolium, but these plants are toxic to the liver and very dangerous for the health of patients, especially floating drugs in the market with similar names to the orthodox medicine. The study results showed high methanol pharmacology in the stem, root and total alkaloid extracts of Crinum latifolium and all of them can inhibit the cell division. In mice models of butt sarcoma and thigh cancer, this extract can minimize the tumor growth and prevent the cancer metastasis. Some alkaloids in this plants with bioactive properties like Lycorin can inhibit the proteins and DNA in mice cells, and simultaneously inhibit the butt tumor implanted in mice. In vitro, Lycorin reduced the viability of tumor cells, stopped the development of the polio virus, inhibit the precursors that is essential for the growth of polio virus.

This is a translation of the article "Nói thêm về Trinh nữ hoàng cung" by Dr. Hoang Xuan Dai on
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